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墨西哥蒙特雷科技大学Rodriguez教授来院合作交流
     
( 来源:生工所  作者:生工所  发布时间:2019-08-21 )

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    黄慧婷介绍了Rodriguez教授的基本情况和来访目的,主要是就流感疫苗后期研发工作商谈合作。楼建林对Rodriguez教授一行表示欢迎,并介绍了我院的基本情况以及在公共卫生和基础医学领域的创新研究工作。
    Rodriguez教授详细介绍了他带来的项目:重组球状结构域流感疫苗(一种低成本、短周期、大规模生产制备方法)。流感是一种危害严重的急性呼吸道传染病,众多疫苗企业都在致力于研发生产成本低、速度快、免疫效果好的新型疫苗。Rodriguez教授团队所在的VacciTech公司通过对血凝素蛋白晶体进行结构模拟和设计,利用酵母稳定表达可溶性重组蛋白。蛋白纯化后免疫雪貂等实验动物能引起较好的免疫应答,并具有一定的保护作用。Rodriguez教授预计基于酵母表达技术的疫苗生产方式与传统流感疫苗的生产方式相比,每支制剂成本大大降低,生产速度快16倍,具有较好的开发应用前景。最后Rodriguez教授和创新中心负责人Alfonso Araujog就项目的后期研发工作提出了合作需求。


    楼建林、郭潮潭与Rodriguez教授等一起探讨了这一流感疫苗制备技术,分析了项目的优势和不足,提出了合理化改进的建议,并就双方的合作空间和合作方式进行探讨,初步达成合作意向,双方将进一步深入交流和洽谈。

 

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